Experimental Studies on the Steroid Aromatization

[experimental Studies of Steroid Diabetes in Rats].

It is well known that adrenal corticosteroids have many biological effects on the carbohydrate metabolism. However, the mechanism of corticosteroids on carbohydrate metabolism has not been completely clarified and remains to be studied. In the present investigation, it was intended to study the effects of dietary carbohydrates on the experimental steroid diabetes induced by Ingles method in whi...

Studies on Steroid Fever

into rabbits. In previous studies this method demonstrated release of leukocyte endogenous pyrogen by etiocholanolone. With two exceptions, steroids known to cause fever in man, such as 11p-OH etiocholanolone and 3a-hydroxy-5P-pregnane-20-one were also pyrogenic in vitro. All steroids tested which are nonpyrogenic in man, such as androsterone, 3,-OH etiocholanolone, and 3a, 1 7a-dihydroxy-5P-pr...

Experimental Studies on the Conical Cap tray Performance

In the present study, experimental investigations about the hydrodynamics of the conical cap tray (ConCap tray) have been carried out. The ConCap tray is an innovative and novel type of cap trays. The effect of the different weir height (2.5, 5 and 7 cm) on the weeping, entrainment and the total pressure drop for the ConCap tray was measured, compared and correlated. The hydraulic experiments w...

Experimental and CFD Studies on the Effect of the Jet Position on Mixing Performance

Methods and Results of Aromatization Studies in Vivo1

In order to characterize aromatization in vivo, an androgen and an estrogen, labeled with different radioactive isotopes, are administered simultaneously, either as a pulse alone or as a pulse followed by a constant infusion of the same radiolabeled steroids. Subsequently, blood samples are obtained at varying time intervals and analyzed for the 3H/14C ratio in nonmetabolized unconjugated estro...